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Other forms of testosterone can have a more rapid effect, such as suspension (pure testosterone in an oil base)and hyperandrogenism, or hyperandrogenism in the non-diet group (with esters). In the hyperandrogenic group, testosterone is absorbed very quickly, whereas in the non-diet group esters have a delayed effect, so esters have the greatest effect at once. Androgenic steroids (testosterone cypionate) can lead to an increased risk of prostate cancer – the reason for this is that androgens reduce testosterone levels in the blood, making them less potent because they can't compete for binding. Testosterone cypionate is also more stable than testosterone enanthate, which means it is easier to store rather than be excreted in a shorter time. Androgens can also be converted into less potent forms of testosterone. For more information about the possible health effects of androgens and their metabolites, see the UK Metabolism and Nutrition section. Androgen resistance (AR) Androgen resistance is when the body becomes resistant to the effects of androgens, which can include: hair loss, reduced bone density, prostate disease, and some cancers. Androgens affect the androgen receptor, which is the receptor that binds androgens. Androgens can alter gene function by inhibiting gene expression on the target cells. There are two types of AR: aromatase (which converts testosterone to estradiol) and androsterone. Androgen resistance is caused by a combination of factors, but there are some common factors and their interaction: Genetics. This affects not only people diagnosed with male pattern baldness, but also people with conditions in which high levels of androgens are not suppressed, such as: cystic fibrosis (CF) androgen deficiency thyroid function disorder female pattern baldness (FPB) Hormone replacement therapy (HRT) Hormone replacement therapy (HRT for men) combined with antiandrogen therapy to suppress androgen production. The presence of one of the following conditions can lead to the development of the higher androgen receptors: androgen receptor positive androgen receptor negative Androgens can also cause other conditions such as: testicular cancer cancer of the prostate (a cancer of the prostate that is spread from man to man and does not affect the liver). More general health concerns regarding androgens Androgens are highly linked to many other diseases and they are Related Article: